Yes, Granite Honeycomb Panel can be used in exterior applications in hot climates. The honeycomb structure of the panel provides thermal insulation and helps to reduce heat transfer, making it suitable for use in hot climates. Additionally, granite is a natural stone that is durable and able to withstand extreme temperatures, making it an ideal choice for exterior applications in hot climates. However, it is important to use high-quality materials and proper installation methods to ensure the longevity and performance of the panels.